Article
The hairless gene of the mouse: relationship of phenotypic effects with expression profile and genotype.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Oct 1999
Cachón-González M B, San-José I, Cano A, Vega J A, García N, Freeman T, Schimmang T, Stoye J P
Abstract excerpt
Various mutations of the hairless (hr) gene of mice result in hair loss and other integument defects. To examine the role of the hr gene in mouse development, the expression profile of hr has been determined by in situ hybridisation and correlated to the nature of genetic changes and morphological abnormalities in different mutant animals. Four variant alleles have been characterised at the molecular level. hr/hr...
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