Article
Molecular and functional aspects of the hairless (hr) gene in laboratory rodents and humans.
Experimental dermatology - 1 Oct 1998
Panteleyev A A, Paus R, Ahmad W, Sundberg J P, Christiano A M
Abstract excerpt
For many years, hairless and rhino mouse mutants have provided a useful and extensively exploited model for studying different aspects of skin physiology, including skin aging, pharmacokinetic evaluation of drug activity and cutaneous absorption, skin carcinogenesis, and skin toxicology. Interest...
Topics
- Alleles
- Alopecia
- Animals
- Gene Expression
- Genes
- Humans
- Mice
- Mice, Hairless
- Mutation
- Proteins
- Transcription Factors
