Article

LDL exposure disrupts mitochondrial function and dynamics in a hippocampal neuronal cell line

2024-06-12

Abstract excerpt

<h4>ABSTRACT</h4> Hypercholesterolemia has been associated with cognitive dysfunction and neurodegenerative disease. Moreover, this metabolic condition disrupts the blood-brain barrier, allowing Low-Density Lipoprotein (LDL) to enter the Central Nervous System. Thus, we investigated the effects of LDL exposure on mitochondrial function in a mouse hippocampal neuronal cell line (HT-22). HT-22 cells were exposed to...

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Literature Corpus work: cc6a265a-a51f-5919-8ac2-c672c6e75b66
DOI: 10.1101/2024.06.12.598647

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