Article

Alcohol and e-cigarette damage alveolar-epithelial barrier by activation of P2X7r and provoke brain endothelial injury via extracellular vesicles

2023-11-14

Abstract excerpt

<h4>Background: </h4> Use of nicotine containing products like electronic cigarettes (e-Cig) and alcohol are associated with mitochondrial membrane depolarization, resulting in the extracellular release of ATP, and mitochondrial DNA (mtDNA), mediating inflammatory responses. While nicotine effects on lungs is well-known, chronic alcohol (ETH) exposure also weakens lung immune responses and cause inflammation. Extr...

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Literature Corpus work: 8c1bc262-3d10-5d62-a2cd-5484873b237f
DOI: 10.21203/rs.3.rs-3552555/v1

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