Article

High fat diet induces brain injury and neuronal apoptosis via down-regulating 3-β hydroxycholesterol 24 reductase (DHCR24)

2022-08-04

Abstract excerpt

Hyperlipidemia (HLP) plays an important role in the pathogenesis of Alzheimer’s disease (AD). However, its pathological molecular mechanism remained unclear. 3β-hydroxysterol Δ24- reductase (DHCR24), a key enzyme in the last step of cholesterol synthesis, has been reported to decrease in the affected areas in the brain of AD patients. In this study, hyperlipidemic mouse model was established to study the effect of...

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Literature Corpus work: 024e6dc9-1c3c-5832-8103-95594b18e1cd
DOI: 10.21203/rs.3.rs-1907255/v1

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High fat diet induces brain injury and neuronal apoptosis via down-regulating 3-β hydroxycholesterol 24 reductase (DHCR24)DOI 10.21203/rs.3.rs-1907255/v1Read

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