Article

Mechanistic Insights into Lipoprotein(a)-induced Cardiomyocyte Ferroptosis via ROS/p38/p53 Signalling

2025-08-08

Abstract excerpt

<title>Abstract</title> <p>Background Lipoprotein(a) [Lp(a)], an LDL-like molecule covalently linked to apolipoprotein (a), is a residual cardiovascular risk factor with established atherogenic and antifibrinolytic properties. However, its direct involvement in cardiomyocyte injury mechanisms remains unclear. In this study, we investigated the effects of Lp(a) on cardiomyocytes. Methods The effects of Lp(a) on ca...

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Literature Corpus work: 4486a357-6911-5d40-b968-424ebd9c95c1
DOI: 10.21203/rs.3.rs-7262720/v1

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