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Article

Joint Analysis of Multiple Traits Using "Optimal" Maximum Heritability Test.

PloS one - 1 Jan 2016

Wang Zhenchuan, Sha Qiuying, Zhang Shuanglin

Abstract excerpt

The joint analysis of multiple traits has recently become popular since it can increase statistical power to detect genetic variants and there is increasing evidence showing that pleiotropy is a widespread phenomenon in complex diseases. Currently, most of existing methods use all of the traits for testing the association between multiple traits and a single variant. However, those methods for association studies...

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PMID: 26950849
DOI: 10.1371/journal.pone.0150975
PMCID: PMC4780705

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