Article
Joint Analysis of Multiple Traits in Rare Variant Association Studies.
Annals of human genetics - 1 May 2016
Wang Zhenchuan, Wang Xuexia, Sha Qiuying, Zhang Shuanglin
Abstract excerpt
The joint analysis of multiple traits has recently become popular since it can increase statistical power to detect genetic variants and there is increasing evidence showing that pleiotropy is a widespread phenomenon in complex diseases. Currently, the majority of existing methods for the joint analysis of multiple traits test association between one common variant and multiple traits. However, the...
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