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Article

Gene- and pathway-based association tests for multiple traits with GWAS summary statistics.

Bioinformatics (Oxford, England) - 1 Jan 2017

Kwak Il-Youp, Pan Wei

Abstract excerpt

To identify novel genetic variants associated with complex traits and to shed new insights on underlying biology, in addition to the most popular single SNP-single trait association analysis, it would be useful to explore multiple correlated (intermediate) traits at the gene- or pathway-level by mining existing single GWAS or meta-analyzed GWAS data. For this purpose, we present an adaptive gene-based test and a...

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Identifiers

PMID: 27592708
DOI: 10.1093/bioinformatics/btw577
PMCID: PMC5198520

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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