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Integrate multiple traits to detect novel trait–gene association using GWAS summary data with an adaptive test approach

22 Nov 2018

Abstract excerpt

MOTIVATION: Genetics hold great promise to precision medicine by tailoring treatment to the individual patient based on their genetic profiles. Toward this goal, many large-scale genome-wide association studies (GWAS) have been performed in the last decade to identify genetic variants associated with various traits and diseases. They have successfully identified tens of thousands of disease-related variants....

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PMID: 30476000
DOI: 10.1093/bioinformatics/bty961

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