Article

Engineering precision zebrafish alleles of human disease

2025-05-21

Abstract excerpt

<h4>SUMMARY</h4> Animal models of human diseases are an essential component of understanding disease pathogenesis and serve as preclinical models for therapeutic evaluation. Recently human patient genome sequencing has defined unique patient variants that result in disease states with different phenotypes than those observed with null alleles. The UAB Center for Precision Animal Modeling (CPAM) serves to analyze...

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Literature Corpus work: 5ae231d2-4c9e-55fd-a67c-6d72e06cb2a5
DOI: 10.1101/2025.05.18.654701

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