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Article

Highly potent anti-SARS-CoV-2 multivalent DARPin therapeutic candidates

2020-08-26

Abstract excerpt

Globally accessible therapeutics against SARS-CoV-2 are urgently needed. Here, we report the generation of the first anti-SARS-CoV-2 DARPin molecules with therapeutic potential as well as rapid large-scale production capabilities. Highly potent multivalent DARPin molecules with low picomolar virus neutralization efficacies were generated by molecular linkage of three different monovalent DARPin molecules. These mu...

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Identifiers and source

Literature Corpus work
caf5f614-64a1-5dbf-891f-5d054969a302
DOI
10.1101/2020.08.25.256339
Open publication

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Highly potent anti-SARS-CoV-2 multivalent DARPin therapeutic candidatesDOI 10.1101/2020.08.25.256339
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