Article
Broad‐Spectrum Engineered Multivalent Nanobodies Against SARS‐CoV‐1/2
7 Oct 2024
Abstract excerpt
SARS-CoV-2 Omicron sublineages escape most preclinical/clinical neutralizing antibodies in development, suggesting that previously employed antibody screening strategies are not well suited to counteract the rapid mutation of SARS-CoV-2. Therefore, there is an urgent need to screen better broad-spectrum neutralizing antibody. In this study, a comprehensive approach to design broad-spectrum inhibitors against both...
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