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Engineered Multivalent Nanobodies Potently and Broadly Neutralize SARS‐CoV‐2 Variants

1 Aug 2021

Abstract excerpt

The COVID-19 pandemic continues to be a severe threat to human health, especially due to current and emerging SARS-CoV-2 variants with potential to escape humoral immunity developed after vaccination or infection. The development of broadly neutralizing antibodies that engage evolutionarily conserved epitopes on coronavirus spike proteins represents a promising strategy to improve therapy and prophylaxis against...

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PMID: 34514086
DOI: 10.1002/adtp.202100099

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