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Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster models

9 Sept 2022

Abstract excerpt

Nanobodies offer several potential advantages over mAbs for the control of SARS-CoV-2. Their ability to access cryptic epitopes conserved across SARS-CoV-2 variants of concern (VoCs) and feasibility to engineer modular, multimeric designs, make these antibody fragments ideal candidates for developing broad-spectrum therapeutics against current and continually emerging SARS-CoV-2 VoCs. Here we describe a diverse...

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Bacteriophages and microbial interactions
Monoclonal and Polyclonal Antibodies Research
SARS-CoV-2 and COVID-19 Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36085335
DOI: 10.1038/s42003-022-03866-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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