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A tonsil organoid model reveals Epstein-Barr virus infected germinal center B cell states during primary infection

2026-01-15

Abstract excerpt

Epstein-Barr virus (EBV) colonizes secondary lymphoid tissues to establish persistent infection and is strongly associated with malignancy and autoimmunity. Our understanding of EBV infection biology is hindered by a lack of models that capture infected B cell activity in the lymphoid tissue microenvironment. We therefore developed an EBV human tonsil organoid model to evaluate key B cell states and antiviral resp...

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Literature Corpus work
cae4f7b1-0120-5900-bb55-6739434c573a
DOI
10.64898/2026.01.15.699764
Open publication

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A tonsil organoid model reveals Epstein-Barr virus infected germinal center B cell states during primary infectionDOI 10.64898/2026.01.15.699764
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