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EBV Latency Programs: Molecular and Epigenetic Regulation and Its Role in Disease Pathogenesis

1 Jul 2025

Abstract excerpt

Epstein-Barr virus (EBV) asymptomatically infects over 95% of the global population, and poses a great threat to human health. This review summarizes the complex mechanisms underlying EBV latency programs and their roles in both viral persistence and disease development. We comprehensively analyze the four distinct latency programs (0, I, II, and III) and their associated gene expression patterns, with particular...

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PMID: 40685972
DOI: 10.1002/jmv.70501

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