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Article

Epstein-Barr virus perpetuates B cell germinal center dynamics and generation of autoimmune-associated phenotypes in vitro.

Frontiers in immunology - 1 Jan 2022

SoRelle Elliott D, Reinoso-Vizcaino Nicolás M, Horn Gillian Q, Luftig Micah A

Abstract excerpt

Human B cells encompass functionally diverse lineages and phenotypic states that contribute to protective as well as pathogenic responses. Epstein-Barr virus (EBV) provides a unique lens for studying heterogeneous B cell responses, given its adaptation to manipulate intrinsic cell programming. EBV promotes the activation, proliferation, and eventual outgrowth of host B cells as immortalized lymphoblastoid cell...

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Identifiers

PMID: 36248899
DOI: 10.3389/fimmu.2022.1001145
PMCID: PMC9554744

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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