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Chronic active Epstein-Barr virus disease originates from infected hematopoietic stem cells

12 Oct 2023

Abstract excerpt

ABSTRACT: Chronic active Epstein-Barr virus (EBV) disease (CAEBV) is a lethal syndrome because of persistent EBV infection. When diagnosed as CAEBV, EBV infection was observed in multiple hematopoietic lineages, but the etiology of CAEBV is still elusive. Bone marrow and peripheral cells derived from 5 patients with CAEBV, 1 patient with EBV-associated hemophagocytic lymphohistiocytosis, and 2 healthy controls...

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PMID: 37824804
DOI: 10.1182/blood.2023021074

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