Article

Distinct stage-specific transcriptional states of B cells in human tonsillar tissue

2021-08-17

Abstract excerpt

<h4>ABSTRACT</h4> B cells within secondary lymphoid tissues encompass a diverse range of activation states and multiple maturation processes that reflect antigen recognition and transition through the germinal center (GC) reaction, in which mature B cells differentiate into memory and antibody-secreting cells (ASCs). Here, using single-cell RNA-seq, we identify distinct activation and maturation profiles of B cel...

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Literature Corpus work: 32fd2126-a904-5a38-9b05-3149d7aaaccc
DOI: 10.1101/2021.08.17.456535

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