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The 3'UTR Polymorphisms in the NLRP3 Gene Associated with the Risk of COPD and Their Putative Effects on the microRNA Mechanism.

Genetic testing and molecular biomarkers - 1 Jun 2024

Wu Huiyan, Huang Chuting, Zhang Yanling, Yang Xin, Peng Liang, Li Weipeng

Abstract excerpt

Aims: Evaluating the association between a single nucleotide polymorphism in the 3' untranslated region (3'UTR) of the miRNA binding site of the NLRP3 gene and the occurrence and development of chronic obstructive pulmonary disease (COPD) and providing information to aid in the early detection and treatment of COPD. Materials and Methods: The regulatory single nuclear polymorphisms (SNPs) located in NLRP3 3'UTR...

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PMID: 38757624
DOI: 10.1089/gtmb.2023.0229

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