Article
Human Leukocyte Antigen and microRNAs as Key Orchestrators of Mild Cognitive Impairment and Alzheimer's Disease: A Systematic Review.
International journal of molecular sciences - 5 Aug 2024
Cătană Cristina Sorina, Marta Monica Mihaela, Văleanu Mădălina, Dican Lucia, Crișan Cătălina Angela
Abstract excerpt
The expression of inflamma-miRs and human leukocyte antigen (HLA) haplotypes could indicate mild cognitive impairment (MCI) and Alzheimer's disease (AD). We used international databases to conduct a systematic review of studies on HLA variants and a meta-analysis of research on microRNAs (miRNAs). We aimed to analyze the discriminative value of HLA variants and miRNAs in MCI, AD and controls to evaluate the...
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