Article
The Association between Polymorphism of NLRP3 rs10754558 and Susceptibility to Arteriosclerosis Obliterans in Chinese Han Male Population
2021-03-19
Abstract excerpt
<title>Abstract</title> <p><bold>Background and aims:</bold> Cholesterol crystals have been proved to be able to cause inflammation. NLRP3 inflammasome is activated in response to the accumulation of cholesterol crystals to produce IL-1β, which is associated with atherosclerotic lesions. NLRP3, as part of innate immunity, is involved in the regulation of inflammatory activity described above. The main objective o...
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Identifiers and source
- Literature Corpus work
- 962075fb-1c88-5fe8-9bb0-11c00eeaed19
- DOI
- 10.21203/rs.3.rs-193326/v1
