Article
A Polymorphism Within the 3'UTR of NLRP3 is Associated with Susceptibility for Ischemic Stroke in Chinese Population.
Cellular and molecular neurobiology - 1 Aug 2016
Zhu Zhansheng, Yan Jing, Geng Chunsong, Wang Dagang, Li Chaoyang, Feng Shuai, Wang Huiping
Abstract excerpt
Stroke was regarded as a severe disorder with high morbidity and high mortality worldwide, ischemic stroke (IS) accounts for 85 to 90 % of new increased stroke cases. Partial mechanisms were elucidated by genetic factors including genomic instability such as single nucleotide polymorphism (SNP). Previous reports demonstrated that inflammation was involved in IS, NLRP3 [nucleotide-binding domain (NOD)-like...
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