Article

Determinants of plasma levels of gcg and metabolic impact of glucagon receptor signalling – a UK Biobank study

2023-12-14

Abstract excerpt

<h4>Aims/hypotheses</h4> Glucagon and Glucagon-like peptide-1 (GLP-1) are derived from the same precursor; proglucagon (gcg), and dual agonists of their receptors are currently explored for the treatment of obesity and steatotic liver disease. Elevated levels of endogenous glucagon (hyperglucagonaemia) have been linked with hyperglycaemia in individuals with type 2 diabetes but are also observed in individuals wit...

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Literature Corpus work: cad47d34-4371-57d1-a5b1-938b0fa86e7f
DOI: 10.1101/2023.12.12.23299852

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