Article

Studies to develop a glucagon sensitivity test in humans: The GLUSENTIC study protocol

2022-11-07

Abstract excerpt

<h4>Introduction</h4> A physiological feedback system exists between hepatocytes and the alpha cells termed the liver-alpha cell axis and signifies the role between amino acid-stimulated glucagon secretion and glucagon-stimulated amino acid catabolism. Several reports indicate that metabolic diseases such as non-alcoholic fatty liver disease (NAFLD) disrupts this feedback system, because of impaired glucagon recep...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5829de3a-d79d-5621-8522-afff2d2abfcc
DOI: 10.1101/2022.11.05.22281981

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Studies to develop a glucagon sensitivity test in humans: The GLUSENTIC study protocolDOI 10.1101/2022.11.05.22281981Read

The Liver–α-Cell Axis in Health and in DiseaseSemantic proximity Read

Determinants of plasma levels of gcg and metabolic impact of glucagon receptor signalling – a UK Biobank studySemantic proximity Read

Glycogenic hepatopathy associated with hepatic steatosis in type 1 diabetes Short title: GH associated with MAFLD in T1DMSemantic proximity Read

Efficacy and Safety of GLP-1 Receptor Agonists in Patients with MASLD: A Systematic Review and Meta-analysis of Randomized Clinical TrialsSemantic proximity Read

Thermoacoustic ultrasound assessment of liver steatosis - a novel approach for MASLD diagnosisSemantic proximity Read

Glucagon cell hyperplasia and neoplasia: a recently recognized endocrine receptor diseaseSemantic proximity Read

Glucagon and Amino Acids Are Linked in a Mutual Feedback Cycle: The Liver-α-Cell Axis.Semantic proximity Read

Deleterious mutation V369M in the mouse GCGR gene causes abnormal plasma amino acid levels indicative of a possible liver-α-cell axis.Semantic proximity Read

The Usefulness of Metformin and Ganwei for Metabolic Dysfunction-Associated Steatotic Liver Disease: A Randomized, Placebo-Controlled Trial.Semantic proximity Read

The Effect of Aerobic Exercise on Metabolic Parameters of Patients with Non-Alcoholic Fatty Liver Disease: Systematic Review and Meta-AnalysisSemantic proximity Read

Characterization of a naturally occurring mutation V368M in the human glucagon receptor and its association with metabolic disorders.Semantic proximity Read

ALT/AST ratio: the useful predictive marker for insulin resistanceSemantic proximity Read