Article

PhyDOSE: Design of Follow-up Single-cell Sequencing Experiments of Tumors

2020-04-01

Abstract excerpt

The combination of bulk and single-cell DNA sequencing data of the same tumor enables the inference of high-fidelity phylogenies that form the input to many important downstream analyses in cancer genomics. While many studies simultaneously perform bulk and single-cell sequencing, some studies have analyzed initial bulk data to identify which mutations to target in a follow-up single-cell sequencing experiment, th...

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Literature Corpus work: ca67fa9a-213e-5d10-afa0-bd6665aa3a8b
DOI: 10.1101/2020.03.30.016410

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