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Article

Mutational accessibility of essential genes on chromosome I(left) in Caenorhabditis elegans.

Molecular & general genetics : MGG - 1 Mar 2000

Johnsen R C, Jones S J, Rose A M

Abstract excerpt

We have analyzed a region of approximately 5.4 million base pairs for mutations, which under standard laboratory conditions result in developmental arrest, sterility, or maternal-effect lethality in Caenorhabditis elegans. Lethal mutations were isolated, maintained, and genetically manipulated as homozygotes using sDp2--a duplication of the left half of chromosome I. All of the lethals and rearrangements used in...

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PMID: 10778742
DOI: 10.1007/s004380051165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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