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Article

Dominant maternal-effect mutations causing embryonic lethality in Caenorhabditis elegans.

Genetics - 1 Jun 1990

Mains P E, Sulston I A, Wood W B

Abstract excerpt

We undertook screens for dominant, temperature-sensitive, maternal-effect embryonic-lethal mutations of Caenorhabditis elegans as a way to identify certain classes of genes with early embryonic functions, in particular those that are members of multigene families and those that are required in two copies for normal development. The screens have identified eight mutations, representing six loci. Mutations at three...

Topics

Animals
Caenorhabditis
Chromosome Mapping
Female
Genes, Dominant
Genes, Lethal
Male
Mutation
Phenotype
Temperature

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2379819
DOI: 10.1093/genetics/125.2.351
PMCID: PMC1204025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2379819-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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