Article
Lethal mutations defining 112 complementation groups in a 4.5 Mb sequenced region of Caenorhabditis elegans chromosome III.
Molecular & general genetics : MGG - 1 Nov 1998
Stewart H I, O'Neil N J, Janke D L, Franz N W, Chamberlin H M, Howell A M, Gilchrist E J, Ha T T, Kuervers L M, Vatcher G P, Danielson J L, Baillie D L
Abstract excerpt
The central gene cluster of chromosome III was one of the first regions to be sequenced by the Caenorhabditis elegans genome project. We have performed an essential gene analysis on the left part of this cluster, in the region around dpy-17III balanced by the duplication sDp3. We isolated 151 essential gene mutations and characterized them with regard to their arrest stages. To facilitate positioning of these...
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