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GSTM1 and GSTT1 Double Null Genotypes Determining Cell Fate and Proliferation as Potential Risk Factors of Relapse in Children with Hematological Malignancies after Stem Cell Transplantation.

2021-05-07

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Relapse is the major cause of treatment failure in children with hematological malignancies (HMs) undergoing busulfan (BU)- based allogeneic hematopoietic stem cell transplantation (HSCT). Glutathione S-transferases (GSTs) isoforms that participate in BU detoxification and protect cells against stress and cell death may be linked to post-HSCT outcomes. This stud...

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Literature Corpus work
c9b1e0cc-b741-5233-9feb-bd043efdb495
DOI
10.21203/rs.3.rs-398836/v1
Open publication

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GSTM1 and GSTT1 Double Null Genotypes Determining Cell Fate and Proliferation as Potential Risk Factors of Relapse in Children with Hematological Malignancies after Stem Cell Transplantation.DOI 10.21203/rs.3.rs-398836/v1
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