Article
Improving risk stratification of patients with childhood acute lymphoblastic leukemia: Glutathione-S-Transferases polymorphisms are associated with increased risk of relapse.
Oncotarget - 3 Jan 2017
Leonardi Daiana B, Abbate Mercedes, Riccheri María C, Nuñez Myriam, Alfonso Graciela, Gueron Geraldine, De Siervi Adriana, Vazquez Elba, Cotignola Javier
Abstract excerpt
The inclusion of genotype at Acute Lymphoblastic Leukemia (ALL) diagnosis as a genetic predictor of disease outcome is under constant study. However, results are inconclusive and seem to be population specific. We analyzed the predictive value of germline polymorphisms for childhood ALL relapse and survival. We retrospectively recruited 140 Argentine patients with de novo ALL. Genotypes were analyzed using...
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