Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GSTT1 and GSTM1 polymorphisms predict treatment outcome for acute myeloid leukemia: a systematic review and meta-analysis.

Annals of hematology - 1 Aug 2014

Xiao Qiang, Deng Donghong, Li Hongying, Ye Fanghui, Huang Lulu, Zhang Bing, Ye Bingbing, Mo Zengnan, Yang Xiaobo, Liu Zhenfang

Abstract excerpt

Glutathione S-transferases (GSTs) contribute to the metabolism of different xenobiotics and anticancer drugs and confer protection against oxidative stress thus may influence the treatment outcome of acute myeloid leukemia (AML). Studies regarding the association between GSTT1 and GSTM1 polymorphisms and treatment outcome in AML patients showed an inconsistent result. A systematic review and meta-analysis were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anthracyclines
Share to Antineoplastic Combined Chemotherapy Protocols

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytarabine

Share to Disease-Free Survival

Share to Glutathione Transferase

Share to Inactivation, Metabolic

Share to Pharmacogenetics

Share to Remission Induction

Source

Identifiers

PMID: 24994605
DOI: 10.1007/s00277-014-2050-z

Genes

GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GSTT1 and GSTM1 polymorphisms predict treatment outcome for acute myeloid leukemia: a systematic review and meta-analysis.PMID 24994605Read ↗

Meta-analysis study of glutathione-S-transferases (GSTM1, GSTP1, and GSTT1) gene polymorphisms and risk of acute myeloid leukemia.Semantic proximity Read ↗

[The effects of glutathione S-transferase (GSTT1 and GSTM1) genes polymorphisms on treatment efficacy and prognosis of acute myeloid leukemia].Semantic proximity Read ↗

GSTT1 and GSTM1 polymorphisms predict treatment outcome for breast cancer: a systematic review and meta-analysis.Semantic proximity Read ↗

Glutathione-S-transferase polymorphisms (GSTM1, GSTT1 and GSTP1) and acute leukemia risk in Asians: a meta-analysis.Semantic proximity Read ↗

Glutathione S-transferase gene polymorphisms and susceptibility to acute myeloid leukemia: meta-analyses.Semantic proximity Read ↗

Effect of GSTM1 null genotype on risk of childhood acute leukemia: a meta-analysis.Semantic proximity Read ↗

Risk effects of GST gene polymorphisms in patients with acute myeloid leukemia: a prospective study.Semantic proximity Read ↗

Association of GSTTI and GSTM1 variants with acute myeloid leukemia risk.Semantic proximity Read ↗

Glutathione S-transferase gene polymorphisms and susceptibility to chronic myeloid leukemia.Semantic proximity Read ↗

Deletion of GSTM1 and T1 genes as a risk factor for development of acute leukemia.Semantic proximity Read ↗

Association of GSTM1, GSTT1 and GSTP1 Ile105Val polymorphisms with clinical response to imatinib mesylate treatment among Malaysian chronic myeloid leukaemia patients.Semantic proximity Read ↗

Association of GSTT1 polymorphism with acute myeloid leukemia risk is dependent on smoking status.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.