Article

Mosaic loss of chromosome Y and coronary atherosclerosis in men: insights into sex differences in cardiovascular risk from the SCAPIS study

2025-07-14

Abstract excerpt

<h4>Background</h4> Atherosclerosis predominantly affects men and is the underlying cause of coronary artery disease (CAD) and myocardial infarction (MI). Recent studies show that mosaic loss of chromosome Y (LOY) in blood is associated with all major causes of death, including CAD and MI. However, the relation between LOY and subclinical atherosclerosis remains unclear. This study aims to investigate association...

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Literature Corpus work: c9b15567-ab15-50ba-8360-95719ccf4d61
DOI: 10.1101/2025.07.10.25331326

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