Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome.

doi:10.1016/S0140-6736(11)61453-0

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Article

Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome.

Lancet (London, England) - 10 Mar 2012

Charchar Fadi J, Bloomer Lisa Ds, Barnes Timothy A, Cowley Mark J, Nelson Christopher P, Wang Yanzhong, Denniff Matthew, Debiec Radoslaw, Christofidou Paraskevi, Nankervis Scott, Dominiczak Anna F, Bani-Mustafa Ahmed, Balmforth Anthony J, Hall Alistair S, Erdmann Jeanette, Cambien Francois, Deloukas Panos, Hengstenberg Christian, Packard Chris, Schunkert Heribert, Ouwehand Willem H, Ford Ian, Goodall Alison H, Jobling Mark A, Samani Nilesh J, Tomaszewski Maciej

Abstract excerpt

BACKGROUND: A sexual dimorphism exists in the incidence and prevalence of coronary artery disease--men are more commonly affected than are age-matched women. We explored the role of the Y chromosome in coronary artery disease in the context of this sexual inequity. METHODS: We genotyped 11 markers of the male-specific region of the Y chromosome in 3233 biologically unrelated British men from three cohorts: the...

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PMID: 22325189
DOI: 10.1016/S0140-6736(11)61453-0
PMCID: PMC3314981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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