Hematopoietic loss of Y chromosome and risk of symptomatic peripheral artery disease in men.

doi:10.1016/j.atherosclerosis.2026.121859

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Hematopoietic loss of Y chromosome and risk of symptomatic peripheral artery disease in men.

Atherosclerosis - 1 Sept 2026

Li Chenshu, Tang Dongdong, Hussain Sultana Monira, Liu Kailang, Qiu Peng, Wang Ruihua, Zhou Zhen

Abstract excerpt

BACKGROUND: Mosaic loss of chromosome Y (mLOY) is the most common acquired somatic mutation in men and has been linked to multiple age-related diseases, including cardiovascular diseases. However, its association with symptomatic peripheral artery disease (PAD) remains poorly understood. We aimed to investigate the relationship between hematopoietic mLOY and incident symptomatic PAD in a large population-based...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Y
Share to Clonal Hematopoiesis
Share to Genetic Risk Score
Share to Glomerular Filtration Rate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mosaicism

Share to Peripheral Arterial Disease

Share to UK Biobank

Share to United Kingdom

Source

Open in PubMed

Identifiers

PMID: 42508147
DOI: 10.1016/j.atherosclerosis.2026.121859

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.