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Article

Human CARD9: A Critical Molecule of Fungal Immune Surveillance.

Frontiers in immunology - 1 Jan 2018

Drummond Rebecca A, Franco Luis M, Lionakis Michail S

Abstract excerpt

CARD9 is a signaling adaptor protein that is involved in the transduction of signals from a variety of innate pattern recognition receptors, including the C-type lectin receptors and intracellular NOD receptors and nucleic acid sensors. As a result, CARD9 has been shown in animal models to be an important regulator of immunity to bacteria, fungi, and viruses. Studies in humans with autosomal recessive CARD9...

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Identifiers

PMID: 30127791
DOI: 10.3389/fimmu.2018.01836
PMCID: PMC6088205

Genes

CARD9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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