Article

Dissecting the respective roles of microbiota and host genetics in the susceptibility of <i>Card9</i> <sup>-/-</sup> mice to colitis

2023-01-03

Abstract excerpt

<h4>Background</h4> The etiology of Inflammatory Bowel Disease (IBD) is unclear but involves both genetics and environmental factors, including the gut microbiota. Indeed, exacerbated activation of the gastrointestinal immune system toward the gut microbiota occurs in genetically susceptible hosts and under the influence of the environment. For instance, a majority of IBD susceptibility loci lie within genes invo...

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Literature Corpus work: 5cd01fe0-742f-5609-be04-7e126aa63a9a
DOI: 10.1101/2023.01.03.522555

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