Article

Visualizing alternative mRNA splicing in live mammalian cells with the Riboglow-FLIM sensor

2026-06-08

Abstract excerpt

<title>Abstract</title> <p>Alternative splicing is a widespread phenomenon in eukaryotic gene expression, generating diverse mRNA isoforms with implications in health and disease. Despite its importance, investigating spatiotemporal splicing dynamics in live cells is hindered by the lack of tools to monitor the splicing process on the mRNA level live. Here, we present a split-RNA biosensor to visualize splicing i...

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Literature Corpus work: c9ac6ef0-ba30-543c-bb96-b65a9c755217
DOI: 10.21203/rs.3.rs-8641959/v1

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