Article

Design of a GFP reporter for splicing analysis in mammalian cells

2020-06-03

Abstract excerpt

<title>Abstract</title> <p>Objective: The great majority of eukaryotic genes are formed by exons and introns. Pre-RNA transcripts are extensively processed in the nucleus, with the addition of a cap group at the 5′ end, intron removal and exon ligation (splicing) followed by addition of a poly-A tail at 3′ end. Splicing is performed by specialized macromolecular machinery named spliceosome, composed of five small...

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Literature Corpus work: 4546fd1a-5a58-5764-ae20-203b9c75c9bd
DOI: 10.21203/rs.3.rs-20486/v2

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