Article
A set of genes critical to development is epigenetically poised in mouse germ cells from fetal stages through completion of meiosis
16 Sept 2013
Abstract excerpt
In multicellular organisms, germ cells carry the hereditary material from one generation to the next. Developing germ cells are unipotent gamete precursors, and mature gametes are highly differentiated, specialized cells. However, upon gamete union at fertilization, their genomes drive a totipotent program, giving rise to a complete embryo as well as extraembryonic tissues. The biochemical basis for the ability...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.