Article

ATAC-seq of Low-Input and Cryopreserved Primordial Germ Cells Reveals Functional Enhancers

2025-08-30

Abstract excerpt

Cell fate specification during development is orchestrated by dynamic changes in gene expression, driven by the accessibility of cis-regulatory elements. To profile such functional regulatory elements at the genome-wide level, bulk ATAC-seq is a powerful method. Yet, its application has still been technically limited in rare cell types. Here, we optimized and titrated the ATAC-seq protocol for cultured chicken pri...

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Literature Corpus work: 764fb5cb-fc2b-5d36-877f-30bd0e1e2a97
DOI: 10.1101/2025.08.30.672031

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