Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic reprogramming in mouse primordial germ cells.

Mechanisms of development - 1 Sept 2002

Hajkova Petra, Erhardt Sylvia, Lane Natasha, Haaf Thomas, El-Maarri Osman, Reik Wolf, Walter Jörn, Surani M Azim

Abstract excerpt

Genome-wide epigenetic reprogramming in mammalian germ cells, zygote and early embryos, plays a crucial role in regulating genome functions at critical stages of development. We show here that mouse primordial germ cells (PGCs) exhibit dynamic changes in epigenetic modifications between days 10.5 and 12.5 post coitum (dpc). First, contrary to previous suggestions, we show that PGCs do indeed acquire genome-wide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CpG Islands
Share to DNA Methylation
Share to Embryonic and Fetal Development

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome

Share to Genomic Imprinting

Share to Germ Cells

Share to Mice, Transgenic

Share to Stem Cells

Source

Identifiers

PMID: 12204247
DOI: 10.1016/s0925-4773(02)00181-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic reprogramming in mouse primordial germ cells.PMID 12204247Read ↗

Genome-Wide Reprogramming in the Mouse Germ Line Entails the Base Excision Repair PathwaySemantic proximity Read ↗

DNA methylation dynamics of genomic imprinting in mouse development†Semantic proximity Read ↗

Epigenetic reprogramming in the porcine germ line.Semantic proximity Read ↗

Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cellsSemantic proximity Read ↗

Erasure of DNA methylation, genomic imprints, and epimutations in a primordial germ-cell model derived from mouse pluripotent stem cells.Semantic proximity Read ↗

Erasure of methylation imprinting of Igf2r during mouse primordial germ‐cell developmentSemantic proximity Read ↗

PRDM14 controls X-chromosomal and global epigenetic reprogramming of H3K27me3 in migrating mouse primordial germ cellsSemantic proximity Read ↗

Mammalian epigenomics: reprogramming the genome for development and therapy.Semantic proximity Read ↗

Epigenetic dynamics during preimplantation developmentSemantic proximity Read ↗

Enhancer-associated H3K4 methylation safeguards in vitro germline competenceSemantic proximity Read ↗

Mechanism of mouse germ cell specification: a genetic program regulating epigenetic reprogramming.Semantic proximity Read ↗

Enhancer-associated H3K4 methylation safeguards in vitro germline competence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.