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Kidney Tumoroid Characterisation by Spatial Mass Spectrometry with Same-Section Multiplex Immunofluorescence Uncovers Tumour Microenvironment Lipid Signatures Associated with Aggressive Tumour Phenotypes

2025-04-01

Abstract excerpt

<title>Abstract</title> <p>Renal Cell Carcinoma (RCC) incidence is rising, and treatment remains challenging unless surgery is curative. Tumour heterogeneity contributes to resistance against both chemotherapy and immune checkpoint inhibitors, underscoring the need to better understand the complex tumour microenvironment (TME). While tumour models derived from cancer tissue from patients have advanced cancer rese...

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Literature Corpus work: c99b51ad-1a9a-53a4-a24c-50b8cd3c36b4
DOI: 10.21203/rs.3.rs-6107504/v1

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Kidney Tumoroid Characterisation by Spatial Mass Spectrometry with Same-Section Multiplex Immunofluorescence Uncovers Tumour Microenvironment Lipid Signatures Associated with Aggressive Tumour PhenotypesDOI 10.21203/rs.3.rs-6107504/v1Read

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