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Deep visual multi-omics profiling reveals mechanisms that underlie cancer cell differentiation and aggressiveness in clear cell renal cell carcinoma

2025-02-04

Abstract excerpt

<h4>Summary</h4> Clear cell renal cell carcinoma (ccRCC) exhibits significant intra-tumoral heterogeneity (ITH) at both morphological and genetic levels, complicating treatment and contributing to disease progression. Among these, ccRCCs with focal rhabdoid differentiation stand out as highly aggressive tumors distinguished by cells with unique morphological features. However, the correlation between distinct mor...

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Literature Corpus work
1bf5cfc6-f93c-5e4f-9f82-827572d59877
DOI
10.1101/2025.01.31.635927
Open publication

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Deep visual multi-omics profiling reveals mechanisms that underlie cancer cell differentiation and aggressiveness in clear cell renal cell carcinomaDOI 10.1101/2025.01.31.635927
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