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Pangenome-wide association study reveals selective absence of CRISPR genes (Rv2816c-19c) in drug-resistant<i>Mycobacterium tuberculosis</i>

2024-02-06

Abstract excerpt

<h4>Background</h4> The drug resistance development in Mycobacterium tuberculosis (Mtb) is attributed to the acquisition of mutations in the drug target genes. However, the role of the differential presence of non-essential accessory genes is relatively unexplored and Pan Genome-Wide Association Study (Pan-GWAS) can identify these gene sets that could contribute to drug resistance development in Mtb. <h4>Methodolo...

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Literature Corpus work
7e2d61e1-6213-5f0e-9318-8d37102dcea0
DOI
10.1101/2024.02.06.24302273
Open publication

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Pangenome-wide association study reveals selective absence of CRISPR genes (Rv2816c-19c) in drug-resistant<i>Mycobacterium tuberculosis</i>DOI 10.1101/2024.02.06.24302273
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