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Quantitative measurement of antibiotic resistance in <i>Mycobacterium tuberculosis</i> reveals genetic determinants of resistance and susceptibility in a target gene approach

2021-09-16

Abstract excerpt

The World Health Organization goal of universal drug susceptibility testing for patients with tuberculosis is most likely to be achieved through molecular diagnostics; however, to date these have focused largely on first-line drugs, and always on predicting binary susceptibilities. Here, we used whole genome sequencing and a quantitative microtiter plate assay to relate genomic mutations to minimum inhibitory conc...

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Literature Corpus work
826f79d8-6a9b-5e66-8ff7-cc9d9de11bae
DOI
10.1101/2021.09.14.460353
Open publication

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Quantitative measurement of antibiotic resistance in <i>Mycobacterium tuberculosis</i> reveals genetic determinants of resistance and susceptibility in a target gene approachDOI 10.1101/2021.09.14.460353
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