Article

Chromatin-associated protein complexes link DNA base J and transcription termination in <i>Leishmania</i>

2020-05-28

Abstract excerpt

Unlike most other eukaryotes, Leishmania and other trypanosomatid protozoa have largely eschewed transcriptional control of gene expression; relying instead on post-transcriptional regulation of mRNAs derived from polycistronic transcription units (PTUs). In these parasites, a novel modified nucleotide base (β-D-glucopyranosyloxymethyluracil) known as J plays a critical role in ensuring that transcription termina...

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Literature Corpus work: c967638b-6891-5997-b366-d2d26af90fa0
DOI: 10.1101/2020.05.26.117721

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