Back to search

Article

Identification of a Novel Base J Binding Protein Complex Involved in RNA Polymerase II Transcription Termination in Trypanosomes

2019-08-30

Abstract excerpt

Base J, β-D-glucosyl-hydroxymethyluracil, is a modification of thymine DNA base involved in RNA Polymerase (Pol) II transcription termination in kinetoplastid protozoa. Little is understood regarding how specific thymine residues are targeted for J-modification or the mechanism of J regulated transcription termination. To identify proteins involved in J-synthesis, we expressed a tagged version of the J-glucosyltra...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
407c2800-f563-573a-9c40-d22732d3bb70
DOI
10.1101/753004
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Identification of a Novel Base J Binding Protein Complex Involved in RNA Polymerase II Transcription Termination in TrypanosomesDOI 10.1101/753004
Identification of a novel base J binding protein complex involved in RNA polymerase II transcription termination in trypanosomes.Semantic proximity
Chromatin-associated protein complexes link DNA base J and transcription termination in <i>Leishmania</i>Semantic proximity
Histone H3 Variant Regulates RNA Polymerase II Transcription Termination and Dual Strand Transcription of siRNA Loci in Trypanosoma bruceiSemantic proximity
Two thymidine hydroxylases differentially regulate the formation of glucosylated DNA at regions flanking polymerase II polycistronic transcription units throughout the genome of Trypanosoma bruceiSemantic proximity
Epigenetic Regulation of Polymerase II Transcription Initiation in Trypanosoma cruzi: Modulation of Nucleosome Abundance, Histone Modification, and Polymerase Occupancy by O-Linked Thymine DNA GlucosylationSemantic proximity
Genome-wide overexpression screen reveals a novel transcription termination factor in <i>Trypanosoma brucei</i>Semantic proximity
Protein phosphatase PP1 regulation of RNA polymerase II transcription termination and allelic exclusion of VSG genes in trypanosomes.Semantic proximity
Mono-allelic epigenetic regulation of bi-directional silencing of RNA Polymerase II polycistronic transcription initiation in <i>Trypanosoma brucei</i>Semantic proximity
Mono-allelic epigenetic regulation of polycistronic transcription initiation by RNA polymerase II in Trypanosoma brucei.Semantic proximity
TcZC3HTTP, a regulatory element that contributes to <i>Trypanosoma cruzi</i> cell proliferationSemantic proximity
A novel SNF2 ATPase complex in <i>Trypanosoma brucei</i> with a role in H2A.Z-mediated chromatin remodellingSemantic proximity
The Transcriptome of the Human Pathogen Trypanosoma brucei at Single-Nucleotide ResolutionSemantic proximity
Select a neighboring publication to make it the new centre.