Article

Genome-wide Quantification of Polycistronic Transcription in <i>Leishmania major</i>

2023-11-23

Abstract excerpt

Leishmania major is a human-pathogenic, obligate parasite and the etiological agent of the most prevalent, cutaneous form of leishmaniasis, which is an important neglected, tropical disease with ∼1.2 Mio new infections per year. Leishmania , and the whole order Trypanosomatida, are early eukaryotes with highly diverged gene expression and regulation pathways, setting them apart from their mammalian hosts and from...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bd775ae5-dc22-5e75-b8cf-f8319dfe0579
DOI: 10.1101/2023.11.23.568479

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genome-wide Quantification of Polycistronic Transcription in <i>Leishmania major</i>DOI 10.1101/2023.11.23.568479Read

Genome-wide quantification of polycistronic transcription in Leishmania majorSemantic proximity Read

Chromatin-associated protein complexes link DNA base J and transcription termination in <i>Leishmania</i>Semantic proximity Read

The Transcriptome of the Human Pathogen Trypanosoma brucei at Single-Nucleotide ResolutionSemantic proximity Read

Histone acetylations mark origins of polycistronic transcription in Leishmania majorSemantic proximity Read

The Genome of the Kinetoplastid Parasite, <i>Leishmania major</i>Semantic proximity Read

Identification of sequence-specific promoters driving polycistronic transcription initiation by RNA polymerase II in trypanosomesSemantic proximity Read

Mono-allelic epigenetic regulation of polycistronic transcription initiation by RNA polymerase II in Trypanosoma brucei.Semantic proximity Read

Lights and shadows on gene organization and regulation of gene expression in LeishmaniaSemantic proximity Read

Mono-allelic epigenetic regulation of bi-directional silencing of RNA Polymerase II polycistronic transcription initiation in <i>Trypanosoma brucei</i>Semantic proximity Read

Genome-wide mapping of RPA1 and RAD9 reveals the management of polycistronic transcription, replication initiation, and responses to replication stress in <i>Leishmania</i>Semantic proximity Read

Transcriptomic profiling of gene expression and RNA processing during Leishmania major differentiationSemantic proximity Read

Open chromatin analysis in Trypanosoma cruzi life forms highlights critical differences in genomic compartments and developmental regulation at tDNA lociSemantic proximity Read